Analisis Penggunaan Antibiotika pada Pasien Penyakit Dalam di RSUD Dr. H. Slamet Martodirdjo Pamekasan dengan Metode ATC/DDD

Ridwan, Achmad and Narulita, Lisa and Widyadi, Elvan Dwi and Suharjono, Suharjono (2019) Analisis Penggunaan Antibiotika pada Pasien Penyakit Dalam di RSUD Dr. H. Slamet Martodirdjo Pamekasan dengan Metode ATC/DDD. Jurnal Sains Farmasi & Klinis, 6 (3). pp. 237-242. ISSN 2407-7062

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Abstract

Antimicrobial resistance is a global health problem, it can’t be eliminated but can be slowed down. The wise use of antibiotics is one way to overcome antimicrobial resistance. The Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/ DDD) method is used to assess the quantity of antibiotic use. The purpose of this study was to determine the value of DDD and DU 90% of antibiotics. This research is a descriptive-analytic (cross-sectional) study with retrospective data collection in patients with diseases in RSUD Dr. H. Slamet Martodirdjo Pamekasan during the January-March 2019 period. The inclusion criteria were inpatients with internal medicine using antibiotics. Exclusion criteria were patients using topical antibiotic preparations, patients who died during the study, and pediatric patients (<18 years). The number of samples obtained 482 patients who were further analyzed using the ATC/DDD method. The results showed the total DDD value of antibiotic use was 76.03/100 patient-days with the full length of stay (LOS) of patients being 2270 days. The antibiotic with the highest DDD value was ceftriaxone, 37.56/100 patient-days. While antibiotics that enter the DU 90% segment are ceftriaxone, ciprofloxacin, and levofloxacin, so their use should be monitored because of the potential risk of bacterial resistance to antibiotics

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