Syofyan, Syofyan and Henny, Lucida and Amri, Bakhtiar (2008) Peningkatan Kelarutan Kuersetin Melalui Pembentukan Kompeks Inklusi dengan β-Siklodekstrin. Jurnal Sains dan Teknologi Farmasi, 13 (2).
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Other (Peningkatan Kelarutan Kuersetin Melalui Pembentukan Kompeks Inklusi dengan β-Siklodekstrin)
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Abstract
Quercetin, a chemical cousin of the glycoside rutin from Mqnihot esculenta Crantz, appears to have several biologically activities. Preformulation studies usually associated with a new potent drug substances, includes solubility. The complexation of quercetin by β-cyclodextrin indicated an AL -type diagram with inclusion complex of 1:1 molar ratio and the stability constant (K) of 403,58 M1. the complexation enhance solubility 9-fold compared with that of quercetin, howers it was not efective for liquid and oral phamaceutical applications. Keywords:Quercetin, β-cyclodextrin, complex of inclusion, soIubility.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi |
| Depositing User: | Operator Repo Unand |
| Date Deposited: | 01 Apr 2016 04:09 |
| Last Modified: | 01 Apr 2016 04:10 |
| URI: | http://repo.unand.ac.id/id/eprint/2729 |
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