Andayani, Regina and Satiadarma, Kosasih and Firman, Kurnia (2010) Studi Penggunaan Metode Voltametri “Stripping” Anoda untuk Analisa Kualitatif dan Kuantitatif Senyawa Etinil Estradiol dalam Tablet Kontrasepsi Oral. Jurnal Sains dan Teknologi Farmasi.
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Other (Studi Penggunaan Metode Voltametri “Stripping” Anoda untuk Analisa Kualitatif dan Kuantitatif Senyawa Etinil Estradiol dalam Tablet Kontrasepsi Oral)
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Abstract
Analytical method for the determination of ethinyl estradiol in pure form and in solid pharmaceutical preparations by voltametric technique with a hanging mercury drop electrode had been developed. The analysis of ethinyl estradiol had been performed using differential pulse voltametry. A deposition stage at -500 mV had been applied prior to the analysis followed by an anodic stripping step. Ethinyl estradiol was analyzed in methanol and 0,1 M sodium carbonate buffer of pH 11,5 (1:1). The peak potensials (Ep) of ethinyl estradiol was -348,40 mV. The detection limit of ethinyl estradiol was 2,94 x 10-6 M. ethinyl estradiol in tablet preparations could be identified and assayed without separation. The recovery of ethinyl estradiol of 6 µg/ml in simulation tablet was 98.20 %. Keywords : ethinyl estradiol, voltametric, solid pharmaceutical preparations
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi |
| Depositing User: | Operator Repo Unand |
| Date Deposited: | 30 Mar 2016 04:13 |
| Last Modified: | 30 Mar 2016 04:13 |
| URI: | http://repo.unand.ac.id/id/eprint/1990 |
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