Isolasi Senyawa Kimia Utama dan Uji Aktivitas Antibakteri dari Fraksi Etil Asetat Spon Laut Petrosia nigrans

Dian, Handayani and Esa, Afero and Rustini, Rustini (2009) Isolasi Senyawa Kimia Utama dan Uji Aktivitas Antibakteri dari Fraksi Etil Asetat Spon Laut Petrosia nigrans. Jurnal Sains dan Teknologi Farmasi, 14 (1). ISSN 1410 – 0177

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Abstract

A major compound EA-2-1 has been isolated from etil acetat fraction of marine sponge Petrosia nigrans. Isolation and purification of compound were done by chromatography method followed by recrystallization. EA-2-1 was obtained as white needless (17 mg) melted at 119-1200C. Based on data from chemical reaction with Lieberman Bourchard, ultraviolet and infrared spectra suggested the compound is belong to terpenoid group. The result of antibacterial activity test of EA-2-1 showed the activity against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa and Escherichia coli is low. Keywords : Petrosia nigrans, antimicrobial activity, marine sponge, isolation

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi
Depositing User: Operator Repo Unand
Date Deposited: 30 Mar 2016 03:16
Last Modified: 30 Mar 2016 03:16
URI: http://repo.unand.ac.id/id/eprint/1898

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