Andayani, Regina and Satiadarma, Kosasih and Firman, Kurnia (2010) Studi Penggunana Metode Voltammetri “Stripping” Anoda Untuk Analisis Kualitatif dan Kuantitatif Senyawa Etinil Estradiol Dalam Tablet Kontrasepsi Oral. Jurnal Sains dan Teknologi Farmasi.
|
Text
Jurnal_01.pdf Download (581kB) | Preview |
|
|
Other (Studi Penggunana Metode Voltammetri “Stripping” Anoda Untuk Analisis Kualitatif dan Kuantitatif Senyawa Etinil Estradiol Dalam Tablet Kontrasepsi Oral)
Jurnal_01.ps Download (2MB) | Preview |
Abstract
Analitical method for the determination of estradiol in pure form and solid pharmaceutical preparations by voltammetric techniquewith a hanging mercury drop electrode had been developed. The analysis of ethinyl estradiol had been performed using differential pulse voltammetry. A deposition stage at -500 mV had been applied prior to analysis followed by an anodic stripping step. Ethinyl estradiol was analyzed in methanol and 0.1 M sodium carbonate buffer of pH 11.5 (1 : 1). The peak potensial (Ep) of ethinyl estradiol was -348.40 mV. The detection limit of ethinyl estradiol was 2.94 x 10-6 M. Ethinyl estradiol in tablet preparations could be identified and assyed without separation. The recovery of ethinyl estradiol of 6 µg/ml in simulation tablet was 98.20%. Keywords : ethinyl estradiol, voltammetric, solid prarmaccutical preparation.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi |
| Depositing User: | Operator Repo Unand |
| Date Deposited: | 30 Mar 2016 04:09 |
| Last Modified: | 30 Mar 2016 04:09 |
| URI: | http://repo.unand.ac.id/id/eprint/1984 |
Actions (login required)
 |
View Item |
